KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
15.76
Human Site:
S172
Identified Species:
24.76
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
S172
I
S
T
K
V
P
A
S
K
V
K
D
A
V
E
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
S172
I
S
T
K
V
P
A
S
K
V
K
D
A
M
E
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
S172
I
S
T
K
V
P
P
S
K
V
K
D
A
V
E
Dog
Lupus familis
XP_536242
380
42964
V173
L
S
T
K
V
L
A
V
G
T
N
D
P
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
T164
P
H
A
E
M
P
I
T
K
V
P
S
A
K
T
Rat
Rattus norvegicus
Q6AYK5
386
43662
T167
V
P
T
K
V
P
S
T
K
T
N
G
T
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
T170
V
A
N
K
V
A
S
T
P
P
G
T
D
E
K
Chicken
Gallus gallus
XP_420792
364
42082
N185
G
K
T
E
Q
K
K
N
K
K
E
R
K
E
E
Frog
Xenopus laevis
NP_001086609
360
41600
E168
D
R
P
E
P
P
P
E
A
V
E
E
N
R
K
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
G165
S
R
T
D
L
K
N
G
T
E
E
E
E
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
Q139
M
P
R
N
Q
A
T
Q
V
W
D
I
L
E
K
Honey Bee
Apis mellifera
XP_623803
246
28455
L104
T
E
R
N
F
L
N
L
L
S
K
H
E
N
I
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
K111
N
I
P
R
K
E
A
K
F
I
N
F
L
T
N
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
K180
P
D
G
G
V
Q
E
K
E
M
E
E
K
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
D11
F
N
C
E
V
C
N
D
T
V
P
K
K
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
93.3
93.3
46.6
N.A.
26.6
40
N.A.
13.3
20
13.3
6.6
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
100
93.3
53.3
N.A.
46.6
60
N.A.
46.6
40
40
33.3
N.A.
13.3
6.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
14
27
0
7
0
0
0
27
7
0
% A
% Cys:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
0
0
0
7
0
0
7
27
7
7
0
% D
% Glu:
0
7
0
27
0
7
7
7
7
7
27
20
14
20
47
% E
% Phe:
7
0
0
0
7
0
0
0
7
0
0
7
0
0
0
% F
% Gly:
7
0
7
7
0
0
0
7
7
0
7
7
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
20
7
0
0
0
0
7
0
0
7
0
7
0
0
7
% I
% Lys:
0
7
0
40
7
14
7
14
40
7
27
7
20
7
20
% K
% Leu:
7
0
0
0
7
14
0
7
7
0
0
0
14
0
0
% L
% Met:
7
0
0
0
7
0
0
0
0
7
0
0
0
7
0
% M
% Asn:
7
7
7
14
0
0
20
7
0
0
20
0
7
14
7
% N
% Pro:
14
14
14
0
7
40
14
0
7
7
14
0
7
0
0
% P
% Gln:
0
0
0
0
14
7
0
7
0
0
0
0
0
0
7
% Q
% Arg:
0
14
14
7
0
0
0
0
0
0
0
7
0
7
0
% R
% Ser:
7
27
0
0
0
0
14
20
0
7
0
7
0
0
0
% S
% Thr:
7
0
47
0
0
0
7
20
14
14
0
7
7
20
14
% T
% Val:
14
0
0
0
54
0
0
7
7
40
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _